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SMILES: FC(F)(c1noc2ncc(cc12)-c1cc[nH]n1)c1ccc2ncccc2c1

InChI Key: InChIKey=JZMQGYPVUGXEDR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 164493   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM164493
PNG
(US9066954, 447)
Show SMILES FC(F)(c1noc2ncc(cc12)-c1cc[nH]n1)c1ccc2ncccc2c1
Show InChI InChI=1S/C19H11F2N5O/c20-19(21,13-3-4-15-11(8-13)2-1-6-22-15)17-14-9-12(16-5-7-24-25-16)10-23-18(14)27-26-17/h1-10H,(H,24,25)
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Similars
US Patent
 12.1 -10.9n/an/an/an/an/a8.027



Amgen Inc.

US Patent


Assay Description
A PCR product covering residues 1058-1365 of c-Met (c-Met kinase domain) is generated from Human Liver QuickClone cDNA (Invitrogen) using forward pri...

US Patent US9066954 (2015)


BindingDB Entry DOI: 10.7270/Q2N878JD
More data for this
Ligand-Target Pair