BDBM164545 US9669029, 116 5,8-Dimethyl-2-[2-(1-methyl-4-pyrimidin-5-yl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrazine
SMILES: CC1=CN=C(C)C2NC(CCc3nc(cn3C)-c3cncnc3)=NN12
InChI Key: InChIKey=WBSHKQILYQHOGV-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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PED10A (Homo sapiens (Human)) | BDBM164545 (US9669029, 116 5,8-Dimethyl-2-[2-(1-methyl-4-pyrim...) | PDB GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 0.440 | n/a | n/a | n/a | n/a | n/a | 25 |
TBA US Patent | Assay Description The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme (sufficient to convert 20-25% of the cyclic nucleotide s... | US Patent US9669029 (2017) BindingDB Entry DOI: 10.7270/Q2BG2M4J | |||||||||||
More data for this Ligand-Target Pair |