BDBM164884 US9067888, 34
SMILES: COc1cc(F)ccc1-c1ccnc(NC(=O)C2CCC(C2)NC(C)=O)c1
InChI Key: InChIKey=FUMJKSZLZJFCAQ-UHFFFAOYSA-N
Data: 10 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cyclin-dependent kinase 1 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.88E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 2 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 913 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 3 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.45E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 5 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.34E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interleukin-1 receptor-associated kinase 1 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 7 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 9 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 alpha (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 99 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 857 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM164884 (US9067888, 34) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
AstraZeneca AB US Patent | Assay Description In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services... | US Patent US9067888 (2015) BindingDB Entry DOI: 10.7270/Q2CR5S4T | |||||||||||
More data for this Ligand-Target Pair |