BDBM165396 US9062043, Table 13, Compound 100::US9062043, Table 13, Compound 64::US9062043, Table 20b, Compound 29
SMILES: OC(=O)c1ccc2c(c1)nc(Nc1cccc(c1)C(F)(F)F)c1nc(NC3CC3)ncc21
InChI Key: InChIKey=UXZATHOFDZQOMY-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM165396 (US9062043, Table 13, Compound 100 | US9062043, Tab...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 10 | n/a | n/a | n/a | n/a | 7.4 | n/a |
SENHWA BIOSCIENCES, INC. US Patent | Assay Description The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr... | US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM165396 (US9062043, Table 13, Compound 100 | US9062043, Tab...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | >750 | n/a | n/a | n/a | n/a | 7.2 | n/a |
SENHWA BIOSCIENCES, INC. US Patent | Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A... | US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Casein kinase II subunit alpha (Homo sapiens (Human)) | BDBM165396 (US9062043, Table 13, Compound 100 | US9062043, Tab...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB US Patent | n/a | n/a | 9 | n/a | n/a | n/a | n/a | 7.2 | n/a |
SENHWA BIOSCIENCES, INC. US Patent | Assay Description Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A... | US Patent US9062043 (2015) BindingDB Entry DOI: 10.7270/Q20G3HWF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |