BDBM16563 (2S)-1-(5-fluoro-2-methoxyphenyl)-3-{[5-(3-methyl-1H-indazol-5-yl)pyridin-3-yl]oxy}propan-2-amine::5-{5-[(2S)-2-amino-3-(5-fluoro-2-methoxyphenyl)propoxy]pyridin-3-yl}-3-methyl-1H-indazole::indazole-pyridine, 13ab

SMILES: COc1ccc(F)cc1C[C@H](N)COc1cncc(c1)-c1ccc2[nH]nc(C)c2c1

InChI Key: InChIKey=LDEDKSSJQNWMBW-IBGZPJMESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase B (Akt 1) (Homo sapiens (Human))	BDBM16563 ((2S)-1-(5-fluoro-2-methoxyphenyl)-3-{[5-(3-methyl-...) Show SMILES COc1ccc(F)cc1C[C@H](N)COc1cncc(c1)-c1ccc2[nH]nc(C)c2c1 |r| Show InChI InChI=1S/C23H23FN4O2/c1-14-21-10-15(3-5-22(21)28-27-14)17-9-20(12-26-11-17)30-13-19(25)8-16-7-18(24)4-6-23(16)29-2/h3-7,9-12,19H,8,13,25H2,1-2H3,(H,27,28)/t19-/m0/s1	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				J Med Chem 50: 2990-3003 (2007) Article DOI: 10.1021/jm0701019 BindingDB Entry DOI: 10.7270/Q24X562F
					More data for this Ligand-Target Pair