BDBM165911 US9067924, 5
SMILES: CC1SCC[C@](C)(N=C1N)c1cc(NC(=O)c2ccc(F)cn2)ccc1F
InChI Key: InChIKey=SBYJDKLBHKDXHY-OWRIGNJKSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-secretase 1 (BACE1) (Mus musculus (Mouse)) | BDBM165911 (US9067924, 5) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2... | US Patent US9067924 (2015) BindingDB Entry DOI: 10.7270/Q2R21049 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta-secretase 2 (BACE2) (Mus musculus (Mouse)) | BDBM165911 (US9067924, 5) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
HOFFMANN-LA ROCHE INC. US Patent | Assay Description An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2... | US Patent US9067924 (2015) BindingDB Entry DOI: 10.7270/Q2R21049 | |||||||||||
More data for this Ligand-Target Pair |