BDBM165916 US9067924, 10

SMILES: CC1(C)C(N)=N[C@@](C)(CCS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F

InChI Key: InChIKey=DCVHGDNPQBRTDK-FQEVSTJZSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165916   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (BACE1) (Mus musculus (Mouse))	BDBM165916 (US9067924, 10) Show SMILES CC1(C)C(N)=N[C@@](C)(CCS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F |r,c:4| Show InChI InChI=1S/C20H22F2N4O3S/c1-19(2)18(23)26-20(3,8-9-30(19,28)29)14-10-13(5-6-15(14)22)25-17(27)16-7-4-12(21)11-24-16/h4-7,10-11H,8-9H2,1-3H3,(H2,23,26)(H,25,27)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	62	n/a	n/a	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2...				US Patent US9067924 (2015) BindingDB Entry DOI: 10.7270/Q2R21049
					More data for this Ligand-Target Pair
Beta-secretase 2 (BACE2) (Mus musculus (Mouse))	BDBM165916 (US9067924, 10) Show SMILES CC1(C)C(N)=N[C@@](C)(CCS1(=O)=O)c1cc(NC(=O)c2ccc(F)cn2)ccc1F |r,c:4| Show InChI InChI=1S/C20H22F2N4O3S/c1-19(2)18(23)26-20(3,8-9-30(19,28)29)14-10-13(5-6-15(14)22)25-17(27)16-7-4-12(21)11-24-16/h4-7,10-11H,8-9H2,1-3H3,(H2,23,26)(H,25,27)/t20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
HOFFMANN-LA ROCHE INC. US Patent					Assay Description An ELISA assay (using a pair of mouse anti-human-TMEM27 antibodies, raised against the extracellular domain of TMEM27) is used for detection of TMEM2...				US Patent US9067924 (2015) BindingDB Entry DOI: 10.7270/Q2R21049
					More data for this Ligand-Target Pair