BDBM165923 US10214524, Example 17::US9067931, 17

SMILES: COc1cccc(c1)-c1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2

InChI Key: InChIKey=QIJLNJPDMZXWEP-FQEVSTJZSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 165923   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM165923 (US10214524, Example 17 | US9067931, 17) Show SMILES COc1cccc(c1)-c1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:20.22,(8.07,-.67,;7.3,-2,;5.76,-2,;4.94,-3.33,;3.4,-3.33,;2.63,-2,;3.4,-.67,;4.94,-.67,;2.63,.67,;3.4,2,;2.63,3.33,;1.09,3.33,;.32,2,;-1.19,1.68,;-1.35,.15,;.06,-.48,;1.09,.67,;-2.68,-.62,;-2.68,-2.16,;-4.02,.15,;-5.35,-.62,;-5.35,-2.16,;-6.68,-2.93,;-8.02,-2.16,;-8.02,-.62,;-6.68,.15,;-5.91,-1.18,;-7.45,-1.6,)| Show InChI InChI=1S/C23H24N2O2S/c1-27-18-6-2-4-16(12-18)19-7-3-5-17-13-21(28-22(17)19)23(26)24-20-14-25-10-8-15(20)9-11-25/h2-7,12-13,15,20H,8-11,14H2,1H3,(H,24,26)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description Rat brain tissue (hippocampus or whole brain) is homogenized in homogenization buffer (10% w/v, 0.32 M sucrose, 1 mM EDTA, 0.1 mM phenylmethylsulphon...				US Patent US10214524 (2019) BindingDB Entry DOI: 10.7270/Q2JH3PF0
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM165923 (US10214524, Example 17 | US9067931, 17) Show SMILES COc1cccc(c1)-c1cccc2cc(sc12)C(=O)N[C@H]1CN2CCC1CC2 |r,wU:20.22,(8.07,-.67,;7.3,-2,;5.76,-2,;4.94,-3.33,;3.4,-3.33,;2.63,-2,;3.4,-.67,;4.94,-.67,;2.63,.67,;3.4,2,;2.63,3.33,;1.09,3.33,;.32,2,;-1.19,1.68,;-1.35,.15,;.06,-.48,;1.09,.67,;-2.68,-.62,;-2.68,-2.16,;-4.02,.15,;-5.35,-.62,;-5.35,-2.16,;-6.68,-2.93,;-8.02,-2.16,;-8.02,-.62,;-6.68,.15,;-5.91,-1.18,;-7.45,-1.6,)| Show InChI InChI=1S/C23H24N2O2S/c1-27-18-6-2-4-16(12-18)19-7-3-5-17-13-21(28-22(17)19)23(26)24-20-14-25-10-8-15(20)9-11-25/h2-7,12-13,15,20H,8-11,14H2,1H3,(H,24,26)/t20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	17	-9.85	n/a	n/a	n/a	n/a	n/a	7.4	4
BAYER INTELLECTUAL PROPERTY GMBH US Patent					Assay Description The [3H]-methyllycaconitine binding assay is a modification of the method described by Davies et al. in Neuropharmacol. 1999, 38, 679-690.Rat brain t...				US Patent US9067931 (2015) BindingDB Entry DOI: 10.7270/Q2M907F1
					More data for this Ligand-Target Pair