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SMILES: FC(F)(F)Oc1ccc(CN(c2nc3ccccn3c2Cl)S(=O)(=O)c2ccccc2)cc1

InChI Key: InChIKey=CAYNQLSIFYQNMQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 165941   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential M8 protein


(Canis lupus familiaris (Dog))		BDBM165941
PNG
(US9067935, 3)
Show SMILES FC(F)(F)Oc1ccc(CN(c2nc3ccccn3c2Cl)S(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C21H15ClF3N3O3S/c22-19-20(26-18-8-4-5-13-27(18)19)28(32(29,30)17-6-2-1-3-7-17)14-15-9-11-16(12-10-15)31-21(23,24)25/h1-13H,14H2
PDB

KEGG

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 1.80n/an/an/an/an/a25



Janssen Pharmaceutica, NV

US Patent


Assay Description
The functional activity of compounds of the formula (I) was determined by measuring changes in intracellular calcium concentration using a Ca2+-sensi...

US Patent US9067935 (2015)


BindingDB Entry DOI: 10.7270/Q2GH9GQR
More data for this
Ligand-Target Pair