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BDBM167405 US9073882, 86

SMILES: Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc(C#N)c(F)c2Cl)CC1

InChI Key: InChIKey=GMOVOAFQRUKOBK-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167405   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-sensitive inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM167405
PNG
(US9073882, 86)
Show SMILES Cc1c2COC(=O)c2ccc1CCN1CCN(CCc2ccc(C#N)c(F)c2Cl)CC1
Show InChI InChI=1S/C24H25ClFN3O2/c1-16-17(4-5-20-21(16)15-31-24(20)30)6-8-28-10-12-29(13-11-28)9-7-18-2-3-19(14-27)23(26)22(18)25/h2-5H,6-13,15H2,1H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 17n/an/an/an/an/a4



Merck Sharp & Dohme Corp.

US Patent


Assay Description
FluxOR Kit Components (Invitrogen F10017) FluxOR Reagent (Component A) FluxOR Assay Buffer (Component B)-10x Concentrate PowerLo...


US Patent US9073882 (2015)


BindingDB Entry DOI: 10.7270/Q21C1VMH
More data for this
Ligand-Target Pair