BDBM167512 US9073917, 11- comparative::US9073917, 9- comparative
SMILES: CCc1[nH]cc2C(C3=C(CNCC3=O)Nc12)c1cccc(Sc2nc3ccccc3[nH]2)c1
InChI Key:
Data: 4 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aurora B/Incenp (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.76E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora kinase A (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Aurora B/Incenp (Homo sapiens (Human)) | BDBM167512 (US9073917, 11- comparative | US9073917, 9- compara...) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 107 | n/a | n/a | n/a | n/a | n/a | n/a |
SANOFI US Patent | Assay Description The capacity to inhibit the kinase activity of the enzyme is estimated by measuring the residual kinase activity of the enzyme in the presence of dif... | US Patent US9073917 (2015) BindingDB Entry DOI: 10.7270/Q2H993X4 | |||||||||||
More data for this Ligand-Target Pair |