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SMILES: Cc1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1

InChI Key: InChIKey=BJQFSJIVYSQLSX-KRWDZBQOSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM16791 (3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...) Show SMILES Cc1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r| Show InChI InChI=1S/C21H21N5O/c1-14-19-9-20(24-12-21(19)26-25-14)16-8-18(11-23-10-16)27-13-17(22)7-15-5-3-2-4-6-15/h2-6,8-12,17H,7,13,22H2,1H3,(H,25,26)/t17-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem 15: 2441-52 (2007) Article DOI: 10.1016/j.bmc.2007.01.010 BindingDB Entry DOI: 10.7270/Q26Q1VGQ
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM16791 (3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...) Show SMILES Cc1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r| Show InChI InChI=1S/C21H21N5O/c1-14-19-9-20(24-12-21(19)26-25-14)16-8-18(11-23-10-16)27-13-17(22)7-15-5-3-2-4-6-15/h2-6,8-12,17H,7,13,22H2,1H3,(H,25,26)/t17-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Zhejiang University Curated by ChEMBL					Assay Description Inhibition of Akt				Eur J Med Chem 44: 4090-7 (2009) Article DOI: 10.1016/j.ejmech.2009.04.050 BindingDB Entry DOI: 10.7270/Q2GT5N74
					More data for this Ligand-Target Pair
cAMP-dependent protein kinase catalytic subunit alpha (Bos taurus (bovine))	BDBM16791 (3-[(2S)-2-amino-3-phenylpropoxy]-5-{3-methyl-1H-py...) Show SMILES Cc1n[nH]c2cnc(cc12)-c1cncc(OC[C@@H](N)Cc2ccccc2)c1 |r| Show InChI InChI=1S/C21H21N5O/c1-14-19-9-20(24-12-21(19)26-25-14)16-8-18(11-23-10-16)27-13-17(22)7-15-5-3-2-4-6-15/h2-6,8-12,17H,7,13,22H2,1H3,(H,25,26)/t17-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...				Bioorg Med Chem 15: 2441-52 (2007) Article DOI: 10.1016/j.bmc.2007.01.010 BindingDB Entry DOI: 10.7270/Q26Q1VGQ
					More data for this Ligand-Target Pair