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SMILES: OC(COc1ncnc2ccccc12)Cn1ccnc1

InChI Key: InChIKey=KTWJKWUVFXXMTI-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 167964   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Vascular endothelial growth factor receptor 2


(Homo sapiens (Human))
BDBM167964
PNG
(1-(1H-Imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-...)
Show SMILES OC(COc1ncnc2ccccc12)Cn1ccnc1
Show InChI InChI=1S/C14H14N4O2/c19-11(7-18-6-5-15-10-18)8-20-14-12-3-1-2-4-13(12)16-9-17-14/h1-6,9-11,19H,7-8H2
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PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 84.3n/an/an/an/a7.225



Nanjing University



Assay Description
VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...


Chem Biol Drug Des 86: 1323-9 (2015)


Article DOI: 10.1111/cbdd.12596
BindingDB Entry DOI: 10.7270/Q2GB22TR
More data for this
Ligand-Target Pair
Platelet-derived growth factor receptor beta


(Homo sapiens (Human))
BDBM167964
PNG
(1-(1H-Imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-...)
Show SMILES OC(COc1ncnc2ccccc12)Cn1ccnc1
Show InChI InChI=1S/C14H14N4O2/c19-11(7-18-6-5-15-10-18)8-20-14-12-3-1-2-4-13(12)16-9-17-14/h1-6,9-11,19H,7-8H2
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 292n/an/an/an/a7.225



Nanjing University



Assay Description
VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...


Chem Biol Drug Des 86: 1323-9 (2015)


Article DOI: 10.1111/cbdd.12596
BindingDB Entry DOI: 10.7270/Q2GB22TR
More data for this
Ligand-Target Pair
Fibroblast growth factor 2


(Homo sapiens (Human))
BDBM167964
PNG
(1-(1H-Imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-...)
Show SMILES OC(COc1ncnc2ccccc12)Cn1ccnc1
Show InChI InChI=1S/C14H14N4O2/c19-11(7-18-6-5-15-10-18)8-20-14-12-3-1-2-4-13(12)16-9-17-14/h1-6,9-11,19H,7-8H2
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 609n/an/an/an/a7.225



Nanjing University



Assay Description
VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...


Chem Biol Drug Des 86: 1323-9 (2015)


Article DOI: 10.1111/cbdd.12596
BindingDB Entry DOI: 10.7270/Q2GB22TR
More data for this
Ligand-Target Pair
Epidermal growth factor receptor


(Homo sapiens (Human))
BDBM167964
PNG
(1-(1H-Imidazol-1-yl)-3-(quinazolin-4-yloxy)propan-...)
Show SMILES OC(COc1ncnc2ccccc12)Cn1ccnc1
Show InChI InChI=1S/C14H14N4O2/c19-11(7-18-6-5-15-10-18)8-20-14-12-3-1-2-4-13(12)16-9-17-14/h1-6,9-11,19H,7-8H2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 483n/an/an/an/a7.225



Nanjing University



Assay Description
VEGFR kinase assays were set up to assess the level of autophosphorylation based on DELFIA/Time-Resolved Fluorometry. 96-well plates were coated at r...


Chem Biol Drug Des 86: 1323-9 (2015)


Article DOI: 10.1111/cbdd.12596
BindingDB Entry DOI: 10.7270/Q2GB22TR
More data for this
Ligand-Target Pair