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SMILES: CC(C)n1c(NC(=O)c2ccc3nc4C(=O)NCCCn4c3c2)nc2ccccc12

InChI Key: InChIKey=TWUMJNHHODMHNL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167970   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))		BDBM167970
PNG
(US9073926, 4)
Show SMILES CC(C)n1c(NC(=O)c2ccc3nc4C(=O)NCCCn4c3c2)nc2ccccc12
Show InChI InChI=1S/C22H22N6O2/c1-13(2)28-17-7-4-3-6-15(17)25-22(28)26-20(29)14-8-9-16-18(12-14)27-11-5-10-23-21(30)19(27)24-16/h3-4,6-9,12-13H,5,10-11H2,1-2H3,(H,23,30)(H,25,26,29)
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Similars
US Patent
n/an/a 33n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...

US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair