BDBM167989 US9073926, 23

SMILES: O=C(Nc1cnc2ccccc2c1)c1ccc2cc3C(=O)NCCCn3c2n1

InChI Key: InChIKey=CTPVTASKZQBESS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167989   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM167989 (US9073926, 23) Show SMILES O=C(Nc1cnc2ccccc2c1)c1ccc2cc3C(=O)NCCCn3c2n1 Show InChI InChI=1S/C21H17N5O2/c27-20(24-15-10-13-4-1-2-5-16(13)23-12-15)17-7-6-14-11-18-21(28)22-8-3-9-26(18)19(14)25-17/h1-2,4-7,10-12H,3,8-9H2,(H,22,28)(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9073926 (2015) BindingDB Entry DOI: 10.7270/Q2BP01J6
					More data for this Ligand-Target Pair