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SMILES: O=C(Nc1cnc2n(ncc2c1)C1CCOCC1)c1ccc2cc3C(=O)NCCCn3c2n1

InChI Key: InChIKey=ZDLIZWHPESZXOR-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 167999   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))		BDBM167999
PNG
(US9073926, 33)
Show SMILES O=C(Nc1cnc2n(ncc2c1)C1CCOCC1)c1ccc2cc3C(=O)NCCCn3c2n1
Show InChI InChI=1S/C23H23N7O3/c31-22(18-3-2-14-11-19-23(32)24-6-1-7-29(19)21(14)28-18)27-16-10-15-12-26-30(20(15)25-13-16)17-4-8-33-9-5-17/h2-3,10-13,17H,1,4-9H2,(H,24,32)(H,27,31)
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Similars
US Patent
n/an/a 20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...

US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair