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SMILES: CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnc2n(CC3CCOC3)ncc2c1

InChI Key: InChIKey=OBKXLPJQBTZBMA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168003   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))		BDBM168003
PNG
(US9073926, 37)
Show SMILES CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnc2n(CC3CCOC3)ncc2c1
Show InChI InChI=1S/C25H27N7O3/c1-25(2)13-27-24(34)20-8-16-3-4-19(30-22(16)31(20)14-25)23(33)29-18-7-17-9-28-32(21(17)26-10-18)11-15-5-6-35-12-15/h3-4,7-10,15H,5-6,11-14H2,1-2H3,(H,27,34)(H,29,33)
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Similars
US Patent
n/an/a 25n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...

US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair