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BDBM168007 US9073926, 41

SMILES: Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)cn1

InChI Key: InChIKey=VGBPXKNBWHOARX-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168007   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168007
PNG
(US9073926, 41)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3n2)cn1
Show InChI InChI=1S/C16H16N6O2/c1-21-9-11(8-18-21)19-15(23)12-4-3-10-7-13-16(24)17-5-2-6-22(13)14(10)20-12/h3-4,7-9H,2,5-6H2,1H3,(H,17,24)(H,19,23)
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MMDB

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PC cid
PC sid
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US Patent
n/an/a 4.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair