BDBM168014 US9073926, 48

SMILES: CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnn(Cc2ccccc2)c1

InChI Key: InChIKey=MISDLVFAYWWZLG-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM168014 (US9073926, 48) Show SMILES CC1(C)CNC(=O)c2cc3ccc(nc3n2C1)C(=O)Nc1cnn(Cc2ccccc2)c1 Show InChI InChI=1S/C24H24N6O2/c1-24(2)14-25-23(32)20-10-17-8-9-19(28-21(17)30(20)15-24)22(31)27-18-11-26-29(13-18)12-16-6-4-3-5-7-16/h3-11,13H,12,14-15H2,1-2H3,(H,25,32)(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	12	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9073926 (2015) BindingDB Entry DOI: 10.7270/Q2BP01J6
					More data for this Ligand-Target Pair