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BDBM168032 US9073926, 66

SMILES: CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NC[C@@H](C)n5c4n3)cnc12

InChI Key: InChIKey=MOAVQHGMQJPAOO-STGVRZAANA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168032   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))
BDBM168032
PNG
(US9073926, 66)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NC[C@@H](C)n5c4n3)cnc12 |r|
Show InChI InChI=1/C21H21N7O2/c1-11(2)28-18-14(9-24-28)6-15(10-22-18)25-20(29)16-5-4-13-7-17-21(30)23-8-12(3)27(17)19(13)26-16/h4-7,9-12H,8H2,1-3H3,(H,23,30)(H,25,29)/t12-/s2
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 4n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair