BDBM168035 US9073926, 69

SMILES: CCn1c(NC(=O)c2ccc3cc4C(=O)NCCC(C)n4c3n2)nc2ccccc12

InChI Key: InChIKey=JSMQKJNGBBRBMO-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM168035 (US9073926, 69) Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)NCCC(C)n4c3n2)nc2ccccc12 Show InChI InChI=1S/C22H22N6O2/c1-3-27-17-7-5-4-6-15(17)25-22(27)26-20(29)16-9-8-14-12-18-21(30)23-11-10-13(2)28(18)19(14)24-16/h4-9,12-13H,3,10-11H2,1-2H3,(H,23,30)(H,25,26,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9073926 (2015) BindingDB Entry DOI: 10.7270/Q2BP01J6
					More data for this Ligand-Target Pair