BDBM168036 US9073926, 70

SMILES: CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C

InChI Key: InChIKey=NQFYAANUFXRFNE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM168036 (US9073926, 70) Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1nc2ccccc2n1CCCN(C)C Show InChI InChI=1S/C25H29N7O2/c1-16-11-12-26-24(34)21-15-17-9-10-19(27-22(17)32(16)21)23(33)29-25-28-18-7-4-5-8-20(18)31(25)14-6-13-30(2)3/h4-5,7-10,15-16H,6,11-14H2,1-3H3,(H,26,34)(H,28,29,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9073926 (2015) BindingDB Entry DOI: 10.7270/Q2BP01J6
					More data for this Ligand-Target Pair