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SMILES: CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(Cc2ccccc2)no1

InChI Key: InChIKey=LPPKYSFULWRWFC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168062   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Ribosomal protein S6 kinase alpha-3


(Homo sapiens (Human))		BDBM168062
PNG
(US9073926, 96)
Show SMILES CC1CCNC(=O)c2cc3ccc(nc3n12)C(=O)Nc1cc(Cc2ccccc2)no1
Show InChI InChI=1S/C23H21N5O3/c1-14-9-10-24-23(30)19-12-16-7-8-18(25-21(16)28(14)19)22(29)26-20-13-17(27-31-20)11-15-5-3-2-4-6-15/h2-8,12-14H,9-11H2,1H3,(H,24,30)(H,26,29)
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Similars
US Patent
n/an/a 13n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...

US Patent US9073926 (2015)


BindingDB Entry DOI: 10.7270/Q2BP01J6
More data for this
Ligand-Target Pair