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SMILES: CCOc1cncnc1Nc1cc(Cl)c2C(=O)NC3(CCCCC3)n2c1=O

InChI Key: InChIKey=WQIYRPKSOUHJTO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168347   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
MAP kinase-interacting serine/threonine-protein kinase 2


(Homo sapiens (Human))		BDBM168347
PNG
(US9669031, 196 8′-chloro-6′-((5-ethoxy...)
Show SMILES CCOc1cncnc1Nc1cc(Cl)c2C(=O)NC3(CCCCC3)n2c1=O
Show InChI InChI=1S/C18H20ClN5O3/c1-2-27-13-9-20-10-21-15(13)22-12-8-11(19)14-16(25)23-18(24(14)17(12)26)6-4-3-5-7-18/h8-10H,2-7H2,1H3,(H,23,25)(H,20,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a<10n/an/an/an/an/a25



eFFECTOR THERAPEUTICS, INC.

US Patent


Assay Description
Compounds are screened for Mnk inhibition using the ADP-Glo kinase assay kit (Promega, catalogue No. V9101). All kinase reactions are performed in Re...

US Patent US9669031 (2017)


BindingDB Entry DOI: 10.7270/Q26Q1VDT
More data for this
Ligand-Target Pair