BDBM168468 US9675593, 28

SMILES: FC(F)(F)Oc1ccc(cc1)-n1c2CCCc2ccc1=O

InChI Key: InChIKey=YANDGYRHVKVPND-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168468   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 (Homo sapiens (Human))	BDBM168468 (US9675593, 28) Show SMILES FC(F)(F)Oc1ccc(cc1)-n1c2CCCc2ccc1=O Show InChI InChI=1S/C15H12F3NO2/c16-15(17,18)21-12-7-5-11(6-8-12)19-13-3-1-2-10(13)4-9-14(19)20/h4-9H,1-3H2	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...				US Patent US9675593 (2017) BindingDB Entry DOI: 10.7270/Q2319T24
					More data for this Ligand-Target Pair