BDBM168505 US9675593, 62

SMILES: CCOc1ccc(c(C)c1)-n1cc(-c2ccc(F)cc2)c2nccnc2c1=O

InChI Key: InChIKey=VKNOSZBCHWCDAY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 168505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Endothelin-1 (Homo sapiens (Human))	BDBM168505 (US9675593, 62) Show SMILES CCOc1ccc(c(C)c1)-n1cc(-c2ccc(F)cc2)c2nccnc2c1=O Show InChI InChI=1S/C22H18FN3O2/c1-3-28-17-8-9-19(14(2)12-17)26-13-18(15-4-6-16(23)7-5-15)20-21(22(26)27)25-11-10-24-20/h4-13H,3H2,1-2H3	UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a
SRMLSC US Patent					Assay Description Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...				US Patent US9675593 (2017) BindingDB Entry DOI: 10.7270/Q2319T24
					More data for this Ligand-Target Pair