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SMILES: N[C@H](COc1cncc(c1)-c1ccc2NC(=O)\C(=C/c3ccccn3)c2c1)Cc1c[nH]c2ccccc12

InChI Key: InChIKey=IJHFVJPXTJREJF-BAAUMNHKSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16943   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM16943
PNG
((3Z)-5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]p...)
Show SMILES N[C@H](COc1cncc(c1)-c1ccc2NC(=O)\C(=C/c3ccccn3)c2c1)Cc1c[nH]c2ccccc12 |r|
Show InChI InChI=1S/C30H25N5O2/c31-22(11-21-16-34-28-7-2-1-6-25(21)28)18-37-24-12-20(15-32-17-24)19-8-9-29-26(13-19)27(30(36)35-29)14-23-5-3-4-10-33-23/h1-10,12-17,22,34H,11,18,31H2,(H,35,36)/b27-14-/t22-/m0/s1
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Similars
Article
PubMed
n/an/a 10.3n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 3424-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.005
BindingDB Entry DOI: 10.7270/Q2K072JJ
More data for this
Ligand-Target Pair