null

SMILES: CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(OC)c3)sc2C1

InChI Key: InChIKey=MOZJYPDRNHDIPZ-UTKZUKDTSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 169498   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169498 (US9079880, 31) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(OC)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O4S/c1-5-13-29-21-10-11-22-25(16-21)37-28(31-22)32-27(34)19-8-6-7-18(14-19)17(2)30-26(33)20-9-12-23(35-3)24(15-20)36-4/h6-9,12,14-15,17,21,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t17-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.2	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM169498 (US9079880, 31) Show SMILES CCCN[C@H]1CCc2nc(NC(=O)c3cccc(c3)[C@@H](C)NC(=O)c3ccc(OC)c(OC)c3)sc2C1 |r| Show InChI InChI=1S/C28H34N4O4S/c1-5-13-29-21-10-11-22-25(16-21)37-28(31-22)32-27(34)19-8-6-7-18(14-19)17(2)30-26(33)20-9-12-23(35-3)24(15-20)36-4/h6-9,12,14-15,17,21,29H,5,10-11,13,16H2,1-4H3,(H,30,33)(H,31,32,34)/t17-,21+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The activity of ROCKII (1-543) kinase was measured utilizing Cambrex PKLight ATP Detection Reagent, a homogeneous assay technology using luciferin-lu...				US Patent US9079880 (2015) BindingDB Entry DOI: 10.7270/Q25X27QJ
					More data for this Ligand-Target Pair