BindingDB logo
myBDB logout

null

SMILES: Cc1cc(\C=C2/C(=O)Nc3ccc(cc23)-c2cncc(OC[C@@H](N)Cc3c[nH]c4ccccc34)c2)oc1C

InChI Key: InChIKey=DADVABODEJAVAI-NUVFXGIKSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16953   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D]


(Homo sapiens (Human))		BDBM16953
PNG
((3Z)-5-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]p...)
Show SMILES Cc1cc(\C=C2/C(=O)Nc3ccc(cc23)-c2cncc(OC[C@@H](N)Cc3c[nH]c4ccccc34)c2)oc1C |r|
Show InChI InChI=1S/C31H28N4O3/c1-18-9-24(38-19(18)2)13-28-27-12-20(7-8-30(27)35-31(28)36)21-11-25(16-33-14-21)37-17-23(32)10-22-15-34-29-6-4-3-5-26(22)29/h3-9,11-16,23,34H,10,17,32H2,1-2H3,(H,35,36)/b28-13-/t23-/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Abbott Laboratories



Assay Description
The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...

Bioorg Med Chem Lett 16: 3424-9 (2006)


Article DOI: 10.1016/j.bmcl.2006.04.005
BindingDB Entry DOI: 10.7270/Q2K072JJ
More data for this
Ligand-Target Pair