BDBM170067 US9073940, 425
SMILES: Fc1cccc2-c3c(CS(=O)(=O)c12)c(nn3[C@H]1CCCN(C1)C1CCCOC1)C(=O)N1CCOCC1
InChI Key: InChIKey=WHLHMMULLULBDZ-ZENAZSQFSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Phosphoinositide 3-kinases (PI3K) (Homo sapiens (Human)) | BDBM170067 (US9073940, 425) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
MERCK SERONO SA US Patent | Assay Description The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass... | US Patent US9073940 (2015) BindingDB Entry DOI: 10.7270/Q2ZC81N2 | |||||||||||
More data for this Ligand-Target Pair |