BDBM170516 US9085540, 56

SMILES: CC(C)c1nc(C(N)=O)c(Nc2cnn(c2)C2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1

InChI Key: InChIKey=GWYBVGHLDQLEPN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 170516   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM170516 (US9085540, 56) Show SMILES CC(C)c1nc(C(N)=O)c(Nc2cnn(c2)C2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C26H32N8O3/c1-5-21(35)29-17-7-6-8-20(13-17)37-26-22(16(2)3)31-23(24(27)36)25(32-26)30-18-14-28-34(15-18)19-9-11-33(4)12-10-19/h5-8,13-16,19H,1,9-12H2,2-4H3,(H2,27,36)(H,29,35)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. US Patent					Assay Description The phosphorylation activity on the peptide substrate of EGFR was investigated using LabChip (trademark) Systems (Caliper Life Sciences, Inc.). For t...				US Patent US9085540 (2015) BindingDB Entry DOI: 10.7270/Q2154FSV
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM170516 (US9085540, 56) Show SMILES CC(C)c1nc(C(N)=O)c(Nc2cnn(c2)C2CCN(C)CC2)nc1Oc1cccc(NC(=O)C=C)c1 Show InChI InChI=1S/C26H32N8O3/c1-5-21(35)29-17-7-6-8-20(13-17)37-26-22(16(2)3)31-23(24(27)36)25(32-26)30-18-14-28-34(15-18)19-9-11-33(4)12-10-19/h5-8,13-16,19H,1,9-12H2,2-4H3,(H2,27,36)(H,29,35)(H,30,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Astellas Pharma Inc. US Patent					Assay Description The phosphorylation activity on the peptide substrate of EGFR was investigated using LabChip (trademark) Systems (Caliper Life Sciences, Inc.). For t...				US Patent US9085540 (2015) BindingDB Entry DOI: 10.7270/Q2154FSV
					More data for this Ligand-Target Pair