BDBM17100 3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carbamoyl]-6-methoxyphenyl}-4-{[(2-hydroxypropyl)(methyl)amino]methyl}thiophene-2-carboxamide::Thiophene-Anthranilamide, 10l

SMILES: COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)O)c1Cl

InChI Key: InChIKey=LAIGHZMYXBMUOH-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17100   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM17100 (3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...) Show SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)O)c1Cl Show InChI InChI=1S/C23H23Cl3N4O4S/c1-12(31)9-30(2)10-13-11-35-21(19(13)26)23(33)29-20-16(6-15(25)7-17(20)34-3)22(32)28-18-5-4-14(24)8-27-18/h4-8,11-12,31H,9-10H2,1-3H3,(H,29,33)(H,27,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.400	-12.7	n/a	n/a	n/a	n/a	n/a	7.5	22
Berlex Biosciences					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				J Med Chem 50: 2967-80 (2007) Article DOI: 10.1021/jm070125f BindingDB Entry DOI: 10.7270/Q2J101F5
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM17100 (3-chloro-N-{4-chloro-2-[(5-chloropyridin-2-yl)carb...) Show SMILES COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)O)c1Cl Show InChI InChI=1S/C23H23Cl3N4O4S/c1-12(31)9-30(2)10-13-11-35-21(19(13)26)23(33)29-20-16(6-15(25)7-17(20)34-3)22(32)28-18-5-4-14(24)8-27-18/h4-8,11-12,31H,9-10H2,1-3H3,(H,29,33)(H,27,28,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex Biosciences					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				J Med Chem 50: 2967-80 (2007) Article DOI: 10.1021/jm070125f BindingDB Entry DOI: 10.7270/Q2J101F5
					More data for this Ligand-Target Pair