BDBM17228 N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3-methyl-1-benzothiophene-2-carboxamide::benzothiophene compound, 5

SMILES: Cc1c(sc2ccccc12)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cc1

InChI Key: InChIKey=PMROMFBTYNBPHW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 17228   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM17228 (N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3...) Show SMILES Cc1c(sc2ccccc12)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C23H16Cl2N2O2S/c1-13-17-4-2-3-5-20(17)30-21(13)23(29)27-19-11-8-15(25)12-18(19)22(28)26-16-9-6-14(24)7-10-16/h2-12H,1H3,(H,26,28)(H,27,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	0.820	-12.3	n/a	n/a	n/a	n/a	n/a	7.5	22
Berlex					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				Bioorg Med Chem 15: 2127-46 (2007) Article DOI: 10.1016/j.bmc.2006.12.019 BindingDB Entry DOI: 10.7270/Q2MS3R1T
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM17228 (N-{4-chloro-2-[(4-chlorophenyl)carbamoyl]phenyl}-3...) Show SMILES Cc1c(sc2ccccc12)C(=O)Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C23H16Cl2N2O2S/c1-13-17-4-2-3-5-20(17)30-21(13)23(29)27-19-11-8-15(25)12-18(19)22(28)26-16-9-6-14(24)7-10-16/h2-12H,1H3,(H,26,28)(H,27,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	>5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Berlex					Assay Description The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...				Bioorg Med Chem 15: 2127-46 (2007) Article DOI: 10.1016/j.bmc.2006.12.019 BindingDB Entry DOI: 10.7270/Q2MS3R1T
					More data for this Ligand-Target Pair