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BDBM172784 US9675593, 685

SMILES: CCOc1ccc(c(C)c1)-n1cc(-c2ccnnc2)c2nn(CC)nc2c1=O

InChI Key: InChIKey=HLADCYPVWJPTHS-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 172784   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Endothelin-1


(Homo sapiens (Human))
BDBM172784
PNG
(US9675593, 685)
Show SMILES CCOc1ccc(c(C)c1)-n1cc(-c2ccnnc2)c2nn(CC)nc2c1=O
Show InChI InChI=1S/C20H20N6O2/c1-4-26-23-18-16(14-8-9-21-22-11-14)12-25(20(27)19(18)24-26)17-7-6-15(28-5-2)10-13(17)3/h6-12H,4-5H2,1-3H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<5.00E+4n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...


US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair