BDBM173008 US9096579, 110

SMILES: CCn1ccc(CNC(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(C)c3[nH]2)n1

InChI Key: InChIKey=WHYBRKFPDIOQPQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173008   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM173008 (US9096579, 110) Show SMILES CCn1ccc(CNC(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(C)c3[nH]2)n1 Show InChI InChI=1S/C24H25N9O/c1-4-33-8-6-17(31-33)12-26-23(34)20-11-16-10-18(9-15(2)22(16)29-20)28-24-25-7-5-19(30-24)21-13-32(3)14-27-21/h5-11,13-14,29H,4,12H2,1-3H3,(H,26,34)(H,25,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM173008 (US9096579, 110) Show SMILES CCn1ccc(CNC(=O)c2cc3cc(Nc4nccc(n4)-c4cn(C)cn4)cc(C)c3[nH]2)n1 Show InChI InChI=1S/C24H25N9O/c1-4-33-8-6-17(31-33)12-26-23(34)20-11-16-10-18(9-15(2)22(16)29-20)28-24-25-7-5-19(30-24)21-13-32(3)14-27-21/h5-11,13-14,29H,4,12H2,1-3H3,(H,26,34)(H,25,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...				US Patent US9096579 (2015) BindingDB Entry DOI: 10.7270/Q2F76B9H
					More data for this Ligand-Target Pair