BindingDB logo
myBDB logout

null

SMILES: CCOc1ccc(c(C)c1)-n1cc(-c2cnn(C)c2)c(NCc2ccc(OCCOC)cc2)cc1=O

InChI Key: InChIKey=FQXFFTDZYSEOPA-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173093   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Endothelin-1


(Homo sapiens (Human))		BDBM173093
PNG
(US9675593, 707)
Show SMILES CCOc1ccc(c(C)c1)-n1cc(-c2cnn(C)c2)c(NCc2ccc(OCCOC)cc2)cc1=O
Show InChI InChI=1S/C28H32N4O4/c1-5-35-24-10-11-27(20(2)14-24)32-19-25(22-17-30-31(3)18-22)26(15-28(32)33)29-16-21-6-8-23(9-7-21)36-13-12-34-4/h6-11,14-15,17-19,29H,5,12-13,16H2,1-4H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a<5.00E+4n/an/an/an/a



SRMLSC

US Patent


Assay Description
Fibroblasts (primary human lung and dermal, HFL-1, 3T3 etc) are seeded in 96-well plates at ~15000 cells/well and serum starved for 0-48 hours. After...

US Patent US9675593 (2017)


BindingDB Entry DOI: 10.7270/Q2319T24
More data for this
Ligand-Target Pair