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SMILES: OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)N(CC1CC1)c1ncc(F)cn1

InChI Key: InChIKey=LTRBJDXUUZQPRC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173248   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM173248
PNG
(US9096595, 51)
Show SMILES OC(=O)Cc1c2CCC(Cn2c2cc(Cl)ccc12)N(CC1CC1)c1ncc(F)cn1
Show InChI InChI=1S/C22H22ClFN4O2/c23-14-3-5-17-18(8-21(29)30)19-6-4-16(12-28(19)20(17)7-14)27(11-13-1-2-13)22-25-9-15(24)10-26-22/h3,5,7,9-10,13,16H,1-2,4,6,8,11-12H2,(H,29,30)
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Similars
US Patent
n/an/a 0.600n/an/an/an/a7.025



Actelion Pharmaceuticals Ltd

US Patent


Assay Description
Binding assay was performed in a final assay volume of 250 ul. First, 25 ul of test compound, previously diluted in Binding-Buffer (Binding-Buffer: 5...

US Patent US9096595 (2015)


BindingDB Entry DOI: 10.7270/Q2X9292G
More data for this
Ligand-Target Pair