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BDBM17352 1,2,4-Triazole Compound, 6::5-(benzylsulfanyl)-N-phenyl-4H-1,2,4-triazol-3-amine

SMILES: C(Sc1nnc(Nc2ccccc2)[nH]1)c1ccccc1

InChI Key: InChIKey=QBUZLNWDECJZMT-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17352   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM17352
PNG
(1,2,4-Triazole Compound, 6 | 5-(benzylsulfanyl)-N-...)
Show SMILES C(Sc1nnc(Nc2ccccc2)[nH]1)c1ccccc1
Show InChI InChI=1S/C15H14N4S/c1-3-7-12(8-4-1)11-20-15-17-14(18-19-15)16-13-9-5-2-6-10-13/h1-10H,11H2,(H2,16,17,18,19)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
0.5 -12.6n/an/an/an/an/a7.522



GSK



Assay Description
MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...


J Med Chem 50: 3777-85 (2007)


Article DOI: 10.1021/jm061182w
BindingDB Entry DOI: 10.7270/Q2B856D7
More data for this
Ligand-Target Pair