BDBM173530 (E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole-2-carbohydrazide (1)

SMILES: Oc1cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc(O)c1O

InChI Key: InChIKey=WTYQQXPXIDCYPE-CAOOACKPSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173530   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Probable maltase-glucoamylase 2 (Homo sapiens)	BDBM173530 ((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...) Show SMILES Oc1cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc(O)c1O Show InChI InChI=1S/C16H13N3O4/c20-13-5-9(6-14(21)15(13)22)8-17-19-16(23)12-7-10-3-1-2-4-11(10)18-12/h1-8,18,20-22H,(H,19,23)/b17-8+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL					Assay Description Inhibition of alpha-glucosidase (unknown origin) using pNPG as substrate preincubated for 10 mins followed by substrate addition measured after 30 mi...				Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025
					More data for this Ligand-Target Pair
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast))	BDBM173530 ((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...) Show SMILES Oc1cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc(O)c1O Show InChI InChI=1S/C16H13N3O4/c20-13-5-9(6-14(21)15(13)22)8-17-19-16(23)12-7-10-3-1-2-4-11(10)18-12/h1-8,18,20-22H,(H,19,23)/b17-8+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Universiti Teknologi MARA (UiTM)					Assay Description The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ...				Bioorg Chem 63: 24-35 (2015) Article DOI: 10.1016/j.bioorg.2015.09.001 BindingDB Entry DOI: 10.7270/Q24Q7SSK
					More data for this Ligand-Target Pair