BDBM173530 (E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole-2-carbohydrazide (1)
SMILES: Oc1cc(\C=N\NC(=O)c2cc3ccccc3[nH]2)cc(O)c1O
InChI Key: InChIKey=WTYQQXPXIDCYPE-CAOOACKPSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Probable maltase-glucoamylase 2 (Homo sapiens) | BDBM173530 ((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...) | UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Babasaheb Bhimrao Ambedkar University (A Central University) Curated by ChEMBL | Assay Description Inhibition of alpha-glucosidase (unknown origin) using pNPG as substrate preincubated for 10 mins followed by substrate addition measured after 30 mi... | Eur J Med Chem 176: 343-377 (2019) Article DOI: 10.1016/j.ejmech.2019.04.025 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
α-glucosidase (Saccharomyces cerevisiae S288c (Baker's yeast)) | BDBM173530 ((E)-N'-(3,4,5-trihydroxybenzylidene)-1H-indole...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universiti Teknologi MARA (UiTM) | Assay Description The 135 µL of 50 mM phosphate saline buffer pH (6.8) was added in the 96-well plate and 20 µL of test sample with 70% DMSO added into the wells. The ... | Bioorg Chem 63: 24-35 (2015) Article DOI: 10.1016/j.bioorg.2015.09.001 BindingDB Entry DOI: 10.7270/Q24Q7SSK | |||||||||||
More data for this Ligand-Target Pair |