BDBM173608 1-[3'-[4-[(Adenine-9-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]uracil (5a)
SMILES: Nc1ncnc2n(Cc3cn(nn3)[C@H]3[C@@H](CO)O[C@H](C3O)n3ccc(=O)[nH]c3=O)cnc12
InChI Key:
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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CAM-RNase A (Bison bison (American bison)) | BDBM173608 (1-[3'-[4-[(Adenine-9-yl)methyl]-1,2,3-triazol-...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 1.59E+5 | -5.26 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of Thessaly | Assay Description The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act... | Bioorg Chem 63: 152-65 (2015) Article DOI: 10.1016/j.bioorg.2015.10.007 BindingDB Entry DOI: 10.7270/Q27H1HCG | |||||||||||
More data for this Ligand-Target Pair |