BDBM173614 9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-1-yl]-b-D-ribofuranosyl]adenine (12b)
SMILES: Cc1cn(Cc2cn(nn2)[C@H]2[C@@H](CO)O[C@H](C2O)N2C=NC3C2N=CN=C3N)c(=O)[nH]c1=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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CAM-RNase A (Bison bison (American bison)) | BDBM173614 (9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...) | PDB MMDB KEGG B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 6.88E+4 | -5.77 | n/a | n/a | n/a | n/a | n/a | n/a | 30 |
University of Thessaly | Assay Description The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act... | Bioorg Chem 63: 152-65 (2015) Article DOI: 10.1016/j.bioorg.2015.10.007 BindingDB Entry DOI: 10.7270/Q27H1HCG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Eosinophil-derived neurotoxin (EDN) (Homo sapiens (Human)) | BDBM173614 (9-[3'-[4-[(Thymine-1-yl)methyl]-1,2,3-triazol-...) | PDB B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | 3.65E+5 | -4.76 | 5.59E+5 | n/a | n/a | n/a | n/a | n/a | 30 |
University of Thessaly | Assay Description The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act... | Bioorg Chem 63: 152-65 (2015) Article DOI: 10.1016/j.bioorg.2015.10.007 BindingDB Entry DOI: 10.7270/Q27H1HCG | |||||||||||
More data for this Ligand-Target Pair |