BDBM173616 5-chloro-1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-1,2,3-triazol-4-yl}methyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (II)

SMILES: OC[C@H]1O[C@H](C(O)[C@H]1O)n1cc(Cn2cc(Cl)c(=O)[nH]c2=O)nn1

InChI Key:

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 173616   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Eosinophil-derived neurotoxin (EDN) (Homo sapiens (Human))	BDBM173616 (5-chloro-1-({1-[(2R,5R)-3,4-dihydroxy-5-(hydroxyme...) Show SMILES OC[C@H]1O[C@H](C(O)[C@H]1O)n1cc(Cn2cc(Cl)c(=O)[nH]c2=O)nn1 |r| Show InChI	PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	4.54E+5	-4.63	5.35E+5	n/a	n/a	n/a	n/a	n/a	30
University of Thessaly					Assay Description The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act...				Bioorg Chem 63: 152-65 (2015) Article DOI: 10.1016/j.bioorg.2015.10.007 BindingDB Entry DOI: 10.7270/Q27H1HCG
					More data for this Ligand-Target Pair