BDBM173618 1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione (IV)
SMILES: Cc1cn([C@@H]2O[C@H](CO)[C@H](O)C2O)c(=O)[nH]c1=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Eosinophil-derived neurotoxin (EDN) (Homo sapiens (Human)) | BDBM173618 (1-[(2R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | Article PubMed | 2.61E+4 | -6.35 | 3.31E+4 | n/a | n/a | n/a | n/a | n/a | 30 |
University of Thessaly | Assay Description The Ribonuclease Activity assay used was adapted from the procedure described by Anfinsen et al. and Slifman et al. Determination of ribonuclease act... | Bioorg Chem 63: 152-65 (2015) Article DOI: 10.1016/j.bioorg.2015.10.007 BindingDB Entry DOI: 10.7270/Q27H1HCG | |||||||||||
More data for this Ligand-Target Pair |