BDBM173785 US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cyclopropyl]-2-[2-(trifluoromethyl)pyrimidin-5-yl]propyl]benzamide::US9649308, (+)2-chloro-N-[3-[1-(trifluoromethyl)cyclopropyl]-2-[2-(trifluoromethyl)pyrimidin-5-yl]propyl]benzamide

SMILES: FC(F)(F)c1ncc(cn1)C(CNC(=O)c1ccccc1Cl)CC1(CC1)C(F)(F)F

InChI Key: InChIKey=UIGGFHHHBJIJNF-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 173785   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173785 (US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cy...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1ccccc1Cl)CC1(CC1)C(F)(F)F Show InChI InChI=1S/C19H16ClF6N3O/c20-14-4-2-1-3-13(14)15(30)27-8-11(7-17(5-6-17)19(24,25)26)12-9-28-16(29-10-12)18(21,22)23/h1-4,9-11H,5-8H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9649308 (2017) BindingDB Entry DOI: 10.7270/Q2BG2R29
					More data for this Ligand-Target Pair
P2X purinoceptor 7 (Homo sapiens (Human))	BDBM173785 (US9102591, (+)2-chloro-N-[3-[1-(trifluoromethyl)cy...) Show SMILES FC(F)(F)c1ncc(cn1)C(CNC(=O)c1ccccc1Cl)CC1(CC1)C(F)(F)F Show InChI InChI=1S/C19H16ClF6N3O/c20-14-4-2-1-3-13(14)15(30)27-8-11(7-17(5-6-17)19(24,25)26)12-9-28-16(29-10-12)18(21,22)23/h1-4,9-11H,5-8H2,(H,27,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	7.4	25
H. Lundbeck A/S US Patent					Assay Description Fluorescent Imaging Plate Reader (FLIPR) assay: Briefly, 293-human or mouse P2X7 stable cells were incubated in sucrose buffer, pH 7.4 [KCl (5 mM), N...				US Patent US9102591 (2015) BindingDB Entry DOI: 10.7270/Q2028Q92
					More data for this Ligand-Target Pair