BDBM17381 1,2,4-Triazole Compound, 39::N-(4-chlorophenyl)-5-{[(3,4-difluorophenyl)methyl]sulfanyl}-4H-1,2,4-triazol-3-amine

SMILES: Fc1ccc(CSc2nnc(Nc3ccc(Cl)cc3)[nH]2)cc1F

InChI Key: InChIKey=YJFCWNYTKZVLEA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17381   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17381 (1,2,4-Triazole Compound, 39 | N-(4-chlorophenyl)-5...) Show SMILES Fc1ccc(CSc2nnc(Nc3ccc(Cl)cc3)[nH]2)cc1F Show InChI InChI=1S/C15H11ClF2N4S/c16-10-2-4-11(5-3-10)19-14-20-15(22-21-14)23-8-9-1-6-12(17)13(18)7-9/h1-7H,8H2,(H2,19,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...				J Med Chem 50: 3777-85 (2007) Article DOI: 10.1021/jm061182w BindingDB Entry DOI: 10.7270/Q2B856D7
					More data for this Ligand-Target Pair