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BDBM17397 1,2,4-Triazole Compound, 55::5-(benzylsulfanyl)-N-(3,4-dimethoxyphenyl)-4H-1,2,4-triazol-3-amine

SMILES: COc1ccc(Nc2nnc(SCc3ccccc3)[nH]2)cc1OC

InChI Key: InChIKey=OFJZILFQGXSVMM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17397   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM17397
PNG
(1,2,4-Triazole Compound, 55 | 5-(benzylsulfanyl)-N...)
Show SMILES COc1ccc(Nc2nnc(SCc3ccccc3)[nH]2)cc1OC
Show InChI InChI=1S/C17H18N4O2S/c1-22-14-9-8-13(10-15(14)23-2)18-16-19-17(21-20-16)24-11-12-6-4-3-5-7-12/h3-10H,11H2,1-2H3,(H2,18,19,20,21)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
1.70n/an/an/an/an/an/an/an/a



GSK



Assay Description
MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...


J Med Chem 50: 3777-85 (2007)


Article DOI: 10.1021/jm061182w
BindingDB Entry DOI: 10.7270/Q2B856D7
More data for this
Ligand-Target Pair