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BDBM17444 1,2,4-Triazole Compound, 103::5-[(furan-2-ylmethyl)sulfanyl]-N-[2-(propan-2-yl)phenyl]-4H-1,2,4-triazol-3-amine

SMILES: CC(C)c1ccccc1Nc1nnc(SCc2ccco2)[nH]1

InChI Key: InChIKey=QCOPJYWOSKSQNT-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 17444   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (Human))
BDBM17444
PNG
(1,2,4-Triazole Compound, 103 | 5-[(furan-2-ylmethy...)
Show SMILES CC(C)c1ccccc1Nc1nnc(SCc2ccco2)[nH]1
Show InChI InChI=1S/C16H18N4OS/c1-11(2)13-7-3-4-8-14(13)17-15-18-16(20-19-15)22-10-12-6-5-9-21-12/h3-9,11H,10H2,1-2H3,(H2,17,18,19,20)
PDB
MMDB

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3n/an/an/an/an/an/an/an/a



GSK



Assay Description
MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...


J Med Chem 50: 3777-85 (2007)


Article DOI: 10.1021/jm061182w
BindingDB Entry DOI: 10.7270/Q2B856D7
More data for this
Ligand-Target Pair