BDBM175544 US9120744, CDE-058
SMILES: Oc1cc(cc(O)c1O)C(=O)O[C@H]1CCC[C@H](C1)OC(=O)c1cc(O)c(O)c(O)c1
InChI Key: InChIKey=VQONGERHAUPNSO-TXEJJXNPSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Plasminogen activator inhibitor-1 (Homo sapiens (Human)) | BDBM175544 (US9120744, CDE-058) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 50 | n/a | n/a | n/a | n/a | 7.8 | 23 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY US Patent | Assay Description To determine the efficacy of various synthesized PAI-1 inhibitor compounds, a fluorometric plate assay was carried out to measure the half maximal in... | US Patent US9120744 (2015) BindingDB Entry DOI: 10.7270/Q2QF8RN8 | |||||||||||
More data for this Ligand-Target Pair |