BDBM17596 2-(2,1,3-benzothiadiazole-4-sulfonamido)-5-bromobenzoic acid::sulfonamide compound, 2
SMILES: OC(=O)c1cc(Br)ccc1NS(=O)(=O)c1cccc2nsnc12
InChI Key: InChIKey=ZFMGFZJIHDSKHL-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Methionine aminopeptidase 2 (Homo sapiens (Human)) | BDBM17596 (2-(2,1,3-benzothiadiazole-4-sulfonamido)-5-bromobe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Abbott Laboratories | Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with... | Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556 | |||||||||||
More data for this Ligand-Target Pair |